CellCor™

CellCor™

Cell culture is crucial in the research, development, and production of therapeutics in the health care industry. Efficacy, sensitivity, and reproducibility are the key attributes needed for optimal media. After many years of research, Xcell Therapeutics has developed the CellCor™ line of MSC cell culture media products, which began with development of a serum-free defined formulation, and evolved into the launch of our serum-free TRUE chemically defined media. Our CellCor™ media provide superior performance while maintaining strong safety and quality assurance through our strict adherence to good manufacturing practices.

CellCor

200+ Compounds
Optimal Composition
Mass Production Process

Product

CellCor™
SFD MSC
CellCor™
CD MSC

Class

Serum-Free
Fully Defined
Serum-Free
Chemically Defined

Cell Type

Human Mesenchymal Stem Cell

Advantages

Proliferation↑
Homogeneity↑
Stemness↑
Genetic Stability↑

Product

CellCor™ SFD MSC

Class

Serum-Free Fully Defined

Cell Type

Human Mesenchymal Stem cell

Advantages

Proliferation↑Homogeneity↑

Product

CellCor™ CD MSC

Class

Serum-Free Chemically defined

Cell Type

Human Mesenchymal Stem cell

Advantages

Stemness ↑Genetic Stability ↑

Xell Therapeutics Catalog number

Catalog No. Product Grade Volume
YSP001 CellCor™ CD MSC RESEARCH (USE ONLY) GRADE 500mL
YSP002 CellCor™ CD MSC GMP GRADE 500mL
YSP009 CellCor™ SFD MSC RESEARCH (USE ONLY) GRADE 500mL
YSP010 CellCor™ SFD MSC GMP GRADE 500mL
Catalong No. YSP001
Product CellCor™ CD MSC
Grade RESEARCH (USE ONLY) GRADE
Volume 500mL
Catalong No. YSP002
Product CellCor™ CD MSC
Grade GMP GRADE
Volume 500mL
Catalong No. YSP009
Product CellCor™ SFD MSC
Grade RESEARCH (USE ONLY) GRADE
Volume 500mL
Catalong No. YSP010
Product CellCor™ SFD MSC
Grade GMP GRADE
Volume 500mL

Xcell Classification of Media

Xcell Classification of Media

Media Abbreviation May Contain Does not Contain
Serum-Based

-

-

  • animal/human sera
    (i.e. FBS)
Serum Free

SF

does not contain

  • no serum/plasma from animal/human

can contain

  • animal/human derived extracts and/or lysates
Xeno Free

XF

does not contain

  • SF + no animal derived extracts and/or lysates
  • human derived extracts and/or lysates

Animal Component Free

Chemically-Defined

ACFCD

  • SF/XF + no extracts and/or lysates
  • animal/human derived recombinants
Serum-Based
abbv.

-

does not contain
  • -
can contain
  • animal/human sera (i.e. FBS)
Serum-Free
abbv.

SF

does not contain
  • no serum/plasma from animal/human
can contain
  • animal/human derived extracts and/or lysates
Xeno-Free
abbv.

XF

does not contain
  • SF + no animal derived extracts and/or lysates
can contain
  • human derived extracts and/or lysates
Animal Component-Free
abbv.

ACF

does not contain
  • SF/XF + no extracts and/or lysates
can contain
  • animal/human derived recombinants
Chemically-Defined
abbv.

CD

does not contain
  • SF/XF + no extracts and/or lysates
can contain
  • animal/human derived recombinants
Q

Under what conditions should the media be thawed?

Incubate media for one hour in room temperature, then water bath at 37℃ until completely thawed.
Q

What types of cells are applicable to CellCor™?

One may culture Adipose-derived (AD)- MSCs, Bone Marrow (BM)- MSCs, Umbilical cord (UC)- MSCs. CellCor™ can also culture Fibroblasts and Derma Papilla Cell (DPC).
Q

Are there any precautions when culturing MSCs?

We recommend to culture the cells in a 37 ℃, 5% CO2 incubator, initial seeding of 4,000~5,000cells/cm2
Q

Is coating necessary when culturing MSCs?

No, CellCor™ does not need coating. However, depending on the testing method or judging by the cells’ status, coat with Gelatin.

Superior

  • Superior Proliferation Rate

    CellCor™ vs. FBS/DMEM vs. other Serum Free Media

    The major strength of CellCor™ is its superior proliferation rate.

    CellCor™ maintained 20~31 hours during the PDT test for 15 passages while the competitions’ media maintained 60~80 hours and 100 hours at the longest.

    Xcell has tested 3 competitors’ serum-free products along with FBS containing media available on the market . None of the 3 commercially available media supported better proliferation rate than CellCor™.

  • Surface Markers

    MSCs can be characterized by surface markers set by International Society for Cellular Therapy guidelines. There are positive CD73, CD90, and CD105 and does not express CD14, CD34, CD45, and HLA-DR.

    Surface Marker Comparison vs Other Serum Free Media

  • Superior Differentiation

    The Mesenchymal stem cell is commonly demonstrated as Multipotent. The capability of differentiation is also the characteristic of MSCs. Tri-lineage differentiations are Adipocyte, Chondrocyte, and Osteocyte.